Human Syndecan-4/SDC4 ELISA Kit PicoKine®

SKU: EK1356

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: SDC4

Specificity: Natural and recombinant human Syndecan-4

Background: Syndecan-4 (SDC4) is a protein that in humans is encoded by the SDC4 gene. The protein is found as a homodimer and is a member of the syndecan proteoglycan family. It is mapped to 20q13.12. Syndecan-4 is one of the four vertebrate syndecans and has a molecular weight of ~20 kDa. It is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. Syndecan-4 also regulates the actin cytoskeleton, cell adhesion, and cell migration. In addition, Syndecan-4 can activate protein kinase C (PKC). The variable domain of syndecan-4 could be a site of self-association. What’s more, Syndecan-4 also binds to phosphatidylinositol (4,5)-bisphosphate (PIP2) through the variable domain and increases PKC activity ten-fold.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E19-E145

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Reference:

Uniprot ID: P31431

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 6385

Protein Name: Syndecan-4

Gene Full Name: syndecan 4

Synonyms: Amphiglycan; Ryudocan core protein; SDC4; SYND4; syndecan 4