Human Supervillin, SVIL ELISA Kit

SKU: E6233Hu

Size:96 Tests-1 Kit

Background:Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation (PubMed:12711699). Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function (PubMed:19109420). May be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:SVIL

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.99ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Supervillin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95425

MASS(Da):247,746

GeneID:6840

Synonyms:Archvillin;MFM10;p205/p250;Supervillin;SVIL

Gene names:SVIL

Standard solution:3200ng/L