Human Squalene synthase,FDFT1 ELISA KIT

SKU: E0751Hu

Size:96 Tests-1 Kit

Background:Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. {ECO:0000269|PubMed:10896663, ECO:0000269|PubMed:24531458}.

Research_area:

Applications:ELISA

Target_protein:FDFT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:22.95ng/L

Detection range:50-3200ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:farnesyl-diphosphate farnesyltransferase 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P37268

MASS(Da):48115

GeneID:2222

Synonyms:FDFT1

Gene names:FDFT1

Standard solution:6400ng/L