Human Sorbin and Sh3 Domain-containing Protein 2, SORBS2 ELISA Kit

SKU: E6204Hu

Size:96 Tests-1 Kit

Background:Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:SORBS2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.81ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Sorbin and SH3 domain-containing protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O94875

MASS(Da):124,108

GeneID:8470

Synonyms:Arg/Abl-interacting protein 2;Arg-binding protein 2;ARGBP2;PRO0618;Sorbin;Sorbin and SH3 domain-containing protein 2;SORBS2

Gene names:SORBS2

Standard solution:4800ng/L