Human Smoothened Homolog, SMO ELISA Kit

SKU: E6185Hu

Size:96 Tests-1 Kit

Background:G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed: 19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:SMO

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.25ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Smoothened Homolog

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q99835

MASS(Da):86,397

GeneID:6608

Synonyms:Protein Gx;SMO;Smoothened homolog

Gene names:SMO

Standard solution:3200ng/L