Human Serum Response Factor, SRF ELISA Kit

SKU: E6166Hu

Size:96 Tests-1 Kit

Background:SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:SRF

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.72ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Serum Response Factor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11831

MASS(Da):51,593

GeneID:6722

Synonyms:CCK4;PTK7;Serum response factor;SRF

Gene names:SRF

Standard solution:2400ng/L