Human Serine palmitoyltransferase, long chain base subunit 2,SPTLC2 ELISA KIT

SKU: E7606Hu

Size:96 Tests-1 Kit

Background:Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis (By similarity). {ECO:0000250|UniProtKB:P97363, ECO:0000269|PubMed:19416851, ECO:0000269|PubMed:19648650, ECO:0000269|PubMed:20920666}.

Research_area:

Applications:ELISA

Target_protein:SPTLC2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.13ng/ml

Detection range:0.25-16ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O15270

MASS(Da):62924

GeneID:9517

Synonyms:SPTLC2 KIAA0526 LCB2

Gene names:SPTLC2

Standard solution:32ng/ml