Human Scavenger Receptor Class B Member 1, SCARB1 ELISA Kit

SKU: E6121Hu

Size:96 Tests-1 Kit

Background:Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed: 12016218, PubMed: 12519372, PubMed: 21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed: 26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed: 12016218). (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry (PubMed: 12356718, PubMed: 12913001, PubMed: 18000990). Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate (PubMed: 12356718). Mediates uptake of M.fortuitum, E.coli and S.aureus (PubMed: 16020694).

Research_area:Microbiology

Applications:ELISA

Target_protein:SCARB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.04ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Scavenger Receptor Class B Member 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8WTV0

MASS(Da):60,878

GeneID:949

Synonyms:CD antigen CD36;CD36 and LIMPII analogous 1;CD36 antigen-like 1;CLA-1;Collagen type I receptor, thrombospondin receptor-like 1;SCARB 1;SCARB1;Scavenger receptor class B member 1;SRB1;SR-BI

Gene names:SCARB1

Standard solution:2400ng/L