Human Reticulocalbin 3, RCN3 ELISA Kit

SKU: E2940Hu

Size:96 Tests-1 Kit

Background:Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed: 16433634, PubMed: 28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed: 28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed: 16433634).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:RCN3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.024ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Reticulocalbin 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96D15

MASS(Da):37,493

GeneID:57333

Synonyms:EF-hand calcium-binding protein RLP49;RCN 3;RCN3;Reticulocalbin-3

Gene names:RCN3

Standard solution:24ng/ml