Human Regulator of G-protein Signaling 2, RGS2 ELISA Kit

SKU: E6074Hu

Size:96 Tests-1 Kit

Background:Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:RGS2

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.96ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Regulator of G-protein signaling 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P41220

MASS(Da):24,382

GeneID:5997

Synonyms:Cell growth-inhibiting gene 31 protein;G0/G1 switch regulatory protein 8;G0S8;Regulator of G-protein signaling 2;RGS2

Gene names:RGS2

Standard solution:4000ng/L