Human Rac GTPase-activating protein 1,RACGAP1 ELISA KIT

SKU: E6052Hu

Size:96 Tests-1 Kit

Background:Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells. {ECO:0000269|PubMed:10979956, ECO:0000269|PubMed:11085985, ECO:0000269|PubMed:11278976, ECO:0000269|PubMed:11782313, ECO:0000269|PubMed:14729465, ECO:0000269|PubMed:15642749, ECO:0000269|PubMed:16103226, ECO:0000269|PubMed:16129829, ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:19468300, ECO:0000269|PubMed:19468302, ECO:0000269|PubMed:23235882, ECO:0000269|PubMed:9497316}.

Research_area:

Applications:ELISA

Target_protein:RACGAP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.14ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Rac GTPase-activating protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H0H5

MASS(Da):71027

GeneID:29127

Synonyms:RACGAP1 KIAA1478 MGCRACGAP

Gene names:RACGAP1

Standard solution:3200ng/L