Human Proviral Integration Site 1, PIM1 ELISA Kit

SKU: E1588Hu

Size:96 Tests-1 Kit

Background:Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed: 15866891, PubMed: 16005298, PubMed: 16208375, PubMed: 16537481, PubMed: 16733527, PubMed: 16766533, PubMed: 16807233, PubMed: 18854159, PubMed: 19249086, PubMed: 22464749, PubMed: 24069340, PubMed: 24351972, PubMed: 24591628, PubMed: 26322679, PubMed: 25326555, PubMed: 28219928). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) Channel subunit ORAI1 (PubMed: 16208375, PubMed: 16537481). Involved in enamel formation (PubMed: 24621671). Activated following interaction with STIMATE, leading to promote STIM1 conformational switch (PubMed: 26322679).

Research_area:Others

Applications:ELISA

Target_protein:STIM1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.021ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Proviral Integration Site 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13586

MASS(Da):77,423

GeneID:6786

Synonyms:STIM 1;STIM1;Stromal interaction molecule 1

Gene names:STIM1

Standard solution:24ng/ml