Human Protein Phosphatase 1 Regulatory Subunit 15A, PPP1R15A ELISA Kit

SKU: E6924Hu

Size:96 Tests-1 Kit

Background:Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

Research_area:Others

Applications:ELISA

Target_protein:PPP1R15A

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.69ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Phosphatase 1 Regulatory Subunit 15A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O75807

MASS(Da):73,478

GeneID:23645

Synonyms:Growth arrest and DNA damage-inducible protein GADD34;Myeloid differentiation primary response protein MyD116 homolog;PPP1R15A;Protein phosphatase 1 regulatory subunit 15A

Gene names:PPP1R15A

Standard solution:4800ng/L