Human Protein FADD,FADD ELISA KIT

SKU: E5965Hu

Size:96 Tests-1 Kit

Background:Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors (PubMed:7538907, PubMed:23955153, PubMed:19118384, PubMed:20935634, PubMed:16762833, PubMed:24025841). The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation (PubMed:7538907, PubMed:19118384, PubMed:20935634, PubMed:16762833). Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (PubMed:16762833). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (PubMed:21109225). {ECO:0000269|PubMed:16762833, ECO:0000269|PubMed:19118384, ECO:0000269|PubMed:20935634, ECO:0000269|PubMed:21109225, ECO:0000269|PubMed:23955153, ECO:0000269|PubMed:24025841, ECO:0000269|PubMed:7538907}.

Research_area:

Applications:ELISA

Target_protein:FADD

Reactivity:Human

Assay type:Sandwich

Sensitivity:34.25ng/L

Detection range:70-15000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein FADD

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13158

MASS(Da):23279

GeneID:8772

Synonyms:FADD MORT1 GIG3

Gene names:FADD

Standard solution:16000ng/L