Human Protein-arginine Deiminase Type-3, PADI3 ELISA Kit

SKU: E4252hu

Size:96 Tests-1 Kit

Background:Peptidyl arginine deiminase, type III, also known as PADI3, is a protein which in humans is encoded by the PADI3 gene. This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PADI3

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.09ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein-arginine deiminase type-3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9ULW8

MASS(Da):74,743

GeneID:51702

Synonyms:PAD3;PADI3;PDI3;Peptidylarginine deiminase III;Protein-arginine deiminase type III;Protein-arginine deiminase type-3;UHS1

Gene names:PADI3

Standard solution:2400ng/L