Human Proliferation Associated Protein 2G4, PA2G4 ELISA Kit

SKU: E2521Hu

Size:96 Tests-1 Kit

Background:May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:PA2G4

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.77ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Proliferation Associated Protein 2G4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UQ80

MASS(Da):43,787

GeneID:5036

Synonyms:Cell cycle protein p38-2G4 homolog;ErbB3-binding protein 1;hG4-1;PA2G4;Proliferation-associated protein 2G4

Gene names:PA2G4

Standard solution:4000ng/L