Human Prkc Apoptosis Wt1 Regulator Protein, PAWR ELISA Kit

SKU: E5909Hu

Size:96 Tests-1 Kit

Background:Pro-apoptotic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:PAWR

Reactivity:Human

Assay type:Sandwich

Sensitivity:6.98ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Prkc Apoptosis Wt1 Regulator Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96IZ0

MASS(Da):36,568

GeneID:5074

Synonyms:Par-4;PAWR;PRKC apoptosis WT1 regulator protein;Prostate apoptosis response 4 protein

Gene names:PAWR

Standard solution:3200ng/L