Human Phospholipase D3,PLD3 ELISA KIT

SKU: E2642Hu

Size:96 Tests-1 Kit

Background:5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30312375). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity). May be important in myotube formation (PubMed:22428023). Plays a role in lysosomal homeostasis (PubMed:28128235). Involved in the regulation of endosomal protein sorting (PubMed:29368044). {ECO:0000250|UniProtKB:O35405, ECO:0000269|PubMed:22428023, ECO:0000269|PubMed:28128235, ECO:0000269|PubMed:29368044, ECO:0000269|PubMed:30312375}.

Research_area:

Applications:ELISA

Target_protein:PLD3

Reactivity:Human

Assay type:Sandwich

Sensitivity:21.45ng/L

Detection range:37.5-2400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Phospholipase D3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8IV08

MASS(Da):54705

GeneID:23646

Synonyms:PLD3

Gene names:PLD3

Standard solution:4800ng/L