Human Peroxisome Proliferators Activator Receptors Alpha, PPAR-A ELISA Kit

SKU: E1450Hu

Size:96 Tests-1 Kit

Background:Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Research_area:Metabolism

Applications:ELISA

Target_protein:PPARA

Reactivity:Human

Assay type:Sandwich

Sensitivity:14.22ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Peroxisome Proliferators Activator Receptors Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q07869

MASS(Da):52,225

GeneID:5465

Synonyms:Nuclear receptor subfamily 1 group C member 1;Peroxisome proliferator-activated receptor alpha;PPARA;PPAR-alpha

Gene names:PPARA

Standard solution:9600ng/L