Human Peptidyl-prolyl cis-trans isomerase FKBP5,FKBP5 ELISA KIT

SKU: E7588Hu

Size:96 Tests-1 Kit

Background:Immunophilin protein with PPIase and co-chaperone activities (PubMed:11350175). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (PubMed:12538866). Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1 (PubMed:28147277). {ECO:0000269|PubMed:11350175, ECO:0000269|PubMed:12538866, ECO:0000269|PubMed:28147277}.

Research_area:

Applications:ELISA

Target_protein:FKBP5

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.55ng/ml

Detection range:1.25-80ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13451

MASS(Da):51212

GeneID:2289

Synonyms:FKBP5 AIG6 FKBP51

Gene names:FKBP5

Standard solution:160ng/ml