Human PD-1 ELISA Kit PicoKine®

SKU: EK0959

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PDCD1

Specificity: Natural and recombinant human PD-1

Background: Programmed cell death protein 1, also called PD-1 or PDCD1 is a protein that in humans is encoded by the PDCD1 gene. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. By fluorescence in situ hybridization, the PDCD1 gene is mapped to 2q37.3. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L25-Q167

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Reference:

Uniprot ID: Q15116

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 5133

Protein Name: Programmed cell death protein 1

Gene Full Name: programmed cell death 1

Synonyms: CD279; hPD 1; hPD l; PD 1; PD1; PD-1; PD-1/CD279; PDCD1; programmed cell death 1; Protein PD 1; SLEB2