Human PAM ELISA Kit PicoKine®

SKU: EK1765

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PAM

Specificity: Natural and recombinant human PAM

Background: Peptidyl-glycine alpha-amidating monooxygenase is an enzyme that catalyzes the biosynthesis of many signaling peptides and, in humans, is encoded by the PAM gene. It is mapped to 5q21.1. This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Immunogen: Expression system for standard: NS0; Immunogen sequence: M1-V817

Clonality:

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Reconstitution:

Reference:

Uniprot ID: P19021

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 5066

Protein Name: Peptidyl-glycine alpha-amidating monooxygenase

Gene Full Name: peptidylglycine alpha-amidating monooxygenase

Synonyms: PAL; PAM; Peptidylamidoglycolate lyase; PHM