Human NT-proANP/NPPA ELISA Kit PicoKine®

SKU: EK1627

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: NPPA

Specificity: Natural and recombinant human NPPA

Background: Atrial natriuretic peptide (ANP), also known as NPPA or PND, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. This gene is mapped to 1p36.22. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). ANP is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes) in response to high blood volume. It acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP has exactly the opposite function of the aldosterone secreted by the zona glomerulosa in regard to its effect on sodium in the kidney – that is, aldosterone stimulates sodium retention and it generates sodium loss.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: N26-R123

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Uniprot ID: P01160

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4878

Protein Name: Natriuretic peptides A

Gene Full Name: natriuretic peptide A

Synonyms: ANF; ANP; ATFB6; Atrial natriuretic factor; Atrial natriuretic peptide; CDD ANF; CDP; NPPA; PND; Prepronatriodilatin