Human Nitric Oxide Synthase-interacting Protein, NOSIP ELISA Kit

SKU: E6495Hu

Size:96 Tests-1 Kit

Background:E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).

Research_area:Others

Applications:ELISA

Target_protein:NOSIP

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.029ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Nitric Oxide Synthase-interacting Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y314

MASS(Da):33,172

GeneID:51070

Synonyms:CGI-25;E3 ubiquitin-protein ligase NOSIP;eNOS-interacting protein;Nitric oxide Synthase-interacting protein;NOSIP;RING-type E3 ubiquitin transferase NOSIP

Gene names:NOSIP

Standard solution:32ng/ml