Human Natural Resistance-associated Macrophage Protein 1, NRAMP-1 ELISA Kit

SKU: E5742Hu

Size:96 Tests-1 Kit

Background:Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

Research_area:Immunology

Applications:ELISA

Target_protein:SLC11A1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.59ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Natural Resistance-Associated Macrophage Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P49279

MASS(Da):59,872

GeneID:6556

Synonyms:Natural resistance-associated macrophage protein 1;NRAMP 1;SLC 11A1;SLC11A1;Solute carrier family 11 member 1

Gene names:SLC11A1

Standard solution:3200ng/L