Human Myosin-Ie,MYO1E ELISA KIT

SKU: E5721Hu

Size:96 Tests-1 Kit

Background:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14. {ECO:0000269|PubMed:11940582, ECO:0000269|PubMed:17257598, ECO:0000269|PubMed:20860408}.

Research_area:

Applications:ELISA

Target_protein:MYO1E

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.39ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Myosin-Ie

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q12965

MASS(Da):127062

GeneID:4643

Synonyms:MYO1E MYO1C

Gene names:MYO1E

Standard solution:2400ng/L