Human Muscleblind-like protein 3,MBNL3 ELISA KIT

SKU: E6800Hu

Size:96 Tests-1 Kit

Background:Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction. {ECO:0000269|PubMed:12297108, ECO:0000269|PubMed:15257297}.

Research_area:

Applications:ELISA

Target_protein:MBNL3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.19ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Muscleblind-like protein 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NUK0

MASS(Da):38532

GeneID:55796

Synonyms:MBNL3 CHCR MBLX39 MBXL

Gene names:MBNL3

Standard solution:48ng/ml