Human Mothers Against Decapentaplegic Homolog 6, SMAD6 ELISA Kit

SKU: E4442Hu

Size:96 Tests-1 Kit

Background:Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.

Research_area:Others

Applications:ELISA

Target_protein:SMAD6

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.72ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Mothers Against Decapentaplegic Homolog 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O43541

MASS(Da):53,497

GeneID:4091

Synonyms:hSMAD6;MAD homolog 6;Mothers against decapentaplegic homolog 6;Mothers against DPP homolog 6;SMAD 6;SMAD family member 6;Smad6

Gene names:SMAD6

Standard solution:2400ng/L