Human Mothers Against Decapentaplegic Homolog 1, SMAD1 ELISA Kit

SKU: E0622Hu

Size:96 Tests-1 Kit

Background:Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Research_area:Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Applications:ELISA

Target_protein:SMAD1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.25ng/ml

Detection range:0.5-150ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Mothers Against Decapentaplegic Homolog 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q15797

MASS(Da):52,260

GeneID:4086

Synonyms:BSP-1;hSMAD1;JV4-1;MAD homolog 1;Mad-related protein 1;Mothers against decapentaplegic homolog 1;Mothers against DPP homolog 1;SMAD 1;SMAD family member 1;SMAD1;Transforming growth factor-beta-signaling protein 1

Gene names:SMAD1

Standard solution:160ng/ml