Human Microtubule-associated Protein Tau, MAPT ELISA Kit

SKU: E6693Hu

Size:96 Tests-1 Kit

Background:Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Research_area:Neuroscience; Signal Transduction; Neuroscience

Applications:ELISA

Target_protein:MAPT

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.62ng/L

Detection range:1-400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:microtubule-associated protein tau

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10636

MASS(Da):78,928

GeneID:4137

Synonyms:DDPAC;FTDP-17;MAPT;MAPTL;Microtubule-associated protein tau;MSTD;MTBT1;Neurofibrillary tangle protein;Paired helical filament-tau;PHF-tau;PPND;PPP1R103;TAU;tau-40

Gene names:MAPT

Standard solution:480ng/L