Human Melanoma-associated Antigen 3, MAGE-3 ELISA Kit

SKU: E5655Hu

Size:96 Tests-1 Kit

Background:Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Research_area:Cancer

Applications:ELISA

Target_protein:MAGEA3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.151ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Melanoma-Associated Antigen 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P43357

MASS(Da):34,747

GeneID:4102

Synonyms:Antigen MZ2-D;Cancer/testis antigen 1.3;CT1.3;MAGE-3 antigen;MAGEA 3;MAGEA3;Melanoma-associated antigen 3

Gene names:MAGEA3

Standard solution:96ng/mL