Human Livin ELISA Kit PicoKine®

SKU: EK1348

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: BIRC7

Specificity: Natural and recombinant human Livin

Background: BIRC7, also called KIAP or Livin, is a protein that in humans is encoded by the BIRC7 gene. This gene is mapped to 20q13.33. It encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. BIRC7 blocked apoptosis induced by BAX induction of cytochrome C release from mitochondria, and it also can block apoptosis induced by chemotherapeutic agents.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: M1-S298

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Reconstitution:

Reference:

Uniprot ID: Q96CA5

Host:

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 79444

Protein Name: Baculoviral IAP repeat-containing protein 7

Gene Full Name: baculoviral IAP repeat containing 7

Synonyms: BIRC7; KIAP; LIVIN; ML IAP; MLIAP; RING finger protein 50; RNF50