Human Kv Channel-interacting Protein 4, KCNIP4 ELISA Kit

SKU: E3830Hu

Size:96 Tests-1 Kit

Background:Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

Research_area:Neuroscience

Applications:ELISA

Target_protein:KCNIP4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.024ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Kv Channel-interacting protein 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6PIL6

MASS(Da):28,729

GeneID:80333

Synonyms:A-type potassium Channel modulatory protein 4;CALP;Calsenilin-like protein;KCHIP4;KCNIP4;Kv Channel-interacting protein 4;Potassium Channel-interacting protein 4

Gene names:KCNIP4

Standard solution:40ng/ml