Human Interleukin-36 Receptor Antagonist Protein, IL1F5 ELISA Kit

SKU: E5527Hu

Size:96 Tests-1 Kit

Background:Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Research_area:Immunology

Applications:ELISA

Target_protein:IL1F5

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.35ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin-36 receptor antagonist protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UBH0

MASS(Da):16,962

GeneID:26525

Synonyms:FIL1;FIL1 delta;FIL1(DELTA);FIL1D;IL-1 delta;IL1F5;IL-1F5;IL1HY1;IL-1HY1;IL1L1;IL-1L1;IL-1ra homolog 1;IL-1-related protein 3;IL-1RP3;IL36RA;IL-36Ra;Interleukin-1 delta;Interleukin-1 family member 5;Interleukin-1 HY1;Interleukin-1 receptor antagonist homolog 1;Interleukin-1-like protein 1;Interleukin-36 receptor antagonist protein;PSORP;PSORS14

Gene names:IL36RN

Standard solution:960ng/L