Human Interleukin-3 Receptor Subunit Alpha, IL3RA ELISA Kit

SKU: E5521Hu

Size:96 Tests-1 Kit

Background:Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.

Research_area:Immunology; Signal Transduction

Applications:ELISA

Target_protein:IL3RA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.048ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin-3 receptor subunit alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P26951

MASS(Da):43,330

GeneID:3563

Synonyms:CD antigen CD123;CD123;hIL-3Ra;IL-3 receptor subunit alpha;IL3R;IL-3R subunit alpha;IL3RA;IL-3RA;IL-3R-alpha;IL3RAY;IL3RX;IL3RY;Interleukin-3 receptor subunit alpha;

Gene names:IL3RA

Standard solution:48ng/ml