Human Insulin-like Growth Factor 2 MRNA-binding Protein 3, IGF2BP3 ELISA Kit

SKU: E5474Hu

Size:96 Tests-1 Kit

Background:RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the Insulin-like growth factor 2 (IGF2) mRNAs.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:IGF2BP3

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.87ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Insulin-like Growth Factor 2 Mrna-Binding Protein 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00425

MASS(Da):63,705

GeneID:10643

Synonyms:hKOC;IGF2 mRNA-binding protein 3;IGF2BP3;IGF-II mRNA-binding protein 3;IMP-3;Insulin-like growth factor 2 mRNA-binding protein 3;KH domain-containing protein overexpressed in cancer;VICKZ family member 3

Gene names:IGF2BP3

Standard solution:4800ng/L