Human Inosine-5-monophosphate Dehydrogenase 2, IMPDH2 ELISA Kit

SKU: E6854Hu

Size:96 Tests-1 Kit

Background:Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (PubMed:7903306, PubMed:7763314). Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism (PubMed:14766016). It may also have a role in the development of malignancy and the growth progression of some tumors.

Research_area:Signal Transduction; Cancer; Metabolism

Applications:ELISA

Target_protein:IMPDH2

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.09ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Inosine-5-monophosphate dehydrogenase 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P12268

MASS(Da):55,805

GeneID:3615

Synonyms:IMP dehydrogenase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH2;IMPDH-II;Inosine-5'-monophosphate dehydrogenase 2

Gene names:IMPDH2

Standard solution:2400ng/L