Human Inhibin B, INHB ELISA Kit

SKU: EA0020Hu

Size:96 Tests-1 Kit

Background:Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely, inhibin downregulates FSH synthesis and inhibits FSH secretion. The existence of inhibin was hypothesized as early as 1916; however, it was not demonstrated to exist until Neena Schwartz and Cornelia Channing's work in the mid 1970s, after which both proteins were molecularly characterized ten years later.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:INH-B

Reactivity:Human

Assay type:Competitive

Sensitivity:3.22ng/L

Detection range:7 - 1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:inhibin B

Species:Human

Storage:2-8ºC

Assay time:2h 30m

UniProt accession:

MASS(Da):

GeneID:

Synonyms:Activin beta B chain;Activin beta-B chain;INH-B;INHBB;INHBB_HUMAN;Inhibin beta 2;Inhibin beta B chain;Inhibin beta B subunit

Gene names:INH-B

Standard solution:1600ng/L