Human Histone Deacetylase 8, HDAC8 ELISA Kit

SKU: E0988Hu

Size:96 Tests-1 Kit

Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Research_area:Others

Applications:ELISA

Target_protein:HDAC8

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.055ng/mL

Detection range:0.1-35ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Histone Deacetylase 8

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BY41

MASS(Da):41,758

GeneID:55869

Synonyms:HD8;HDAC 8;HDAC8;Histone deacetylase 8

Gene names:HDAC8

Standard solution:40ng/mL