Human Hematological and neurological expressed 1 protein,HN1 ELISA KIT

SKU: E5384Hu

Size:96 Tests-1 Kit

Background:Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). {ECO:0000269|PubMed:21323578, ECO:0000269|PubMed:22155408, ECO:0000269|PubMed:25169422, ECO:0000269|PubMed:25450365}.

Research_area:

Applications:ELISA

Target_protein:JPT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:14.63ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Hematological and neurological expressed 1 protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UK76

MASS(Da):16015

GeneID:51155

Synonyms:JPT1 ARM2 HN1

Gene names:JPT1

Standard solution:9600ng/L