Human GIF ELISA Kit PicoKine®

SKU: EK1952

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CBLIF

Specificity: Natural and recombinant human GIF

Background: Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the ileum of the small intestine. In humans, the gastric intrinsic factor protein is encoded by the GIF gene. It is mapped to 11q12.1. Haptocorrin (also known as HC, R protein, and transcobalamin I, TCN1) is another glycoprotein secreted by the salivary glands which binds to vitamin B12. Vitamin B12 is acid sensitive and in binding to transcobalamin I it can safely pass through the acidic stomach to the duodenum. In the less acidic environment of the small intestine, pancreatic enzymes digest the glycoprotein carrier and vitamin B12 can then bind to intrinsic factor

Immunogen: Expression system for standard: NS0; Immunogen sequence: S19-Y417

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Reconstitution:

Reference:

Uniprot ID: P27352

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 2694

Protein Name: Cobalamin binding intrinsic factor

Gene Full Name: cobalamin binding intrinsic factor

Synonyms: CBLIF; GIF; IFMH; Intrinsic factor; IF; INF; TCN3