Human GHR/Growth Hormone R ELISA Kit PicoKine®

SKU: EK1467

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: GHR

Specificity: Natural and recombinant human GHR

Background: Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to chromosome 5p13.1-p12. This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization (the receptor may however also exist as a pre-assembled non-functional dimer) and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature (proportional dwarfism).

Immunogen: Expression system for standard: NS0; Immunogen sequence: A27-Y264

Clonality:

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Reconstitution:

Reference:

Uniprot ID: P10912

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 2690

Protein Name: Growth hormone receptor

Gene Full Name: growth hormone receptor

Synonyms: GH binding protein; GH receptor; GHBP; GHR; Serum binding protein; Somatotropin receptor