Human Gamma-aminobutyric Acid Receptor-associated Protein-like 2, GABARAPL2 ELISA Kit

SKU: E5316Hu

Size:96 Tests-1 Kit

Background:Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity). Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity). It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy (PubMed:20418806, PubMed:23209295). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (PubMed:20418806, PubMed:23209295). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20418806, PubMed:23209295).

Research_area:Neuroscience

Applications:ELISA

Target_protein:GABARAPL2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.046ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Gamma-aminobutyric acid receptor-associated protein-like 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P60520

MASS(Da):13,667

GeneID:11345

Synonyms:ATG8;ATG8C;GABA(A receptor-associated protein-like 2;GABARAPL2;Gamma-aminobutyric acid receptor-associated protein-like 2;Ganglioside expression factor 2;GATE16;GATE-16;GEF2;GEF-2;General protein transport factor p16;Golgi-associated ATPase enhancer of 16 kDa;MAP1 light chain 3-related protein;

Gene names:GABARAPL2

Standard solution:25.6ng/mL