Human Galectin-3, ELISA Kit

SKU: E1951Hu

Size:96 Tests-1 Kit

Background:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

Research_area:Cell Biology

Applications:ELISA

Target_protein:LGALS3

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.49pg/ml

Detection range:5-2000pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Galectin-3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P17931

MASS(Da):26,152

GeneID:3958

Synonyms:35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Gal-3;Galactose-specific lectin 3;Galactoside-binding protein;GALBP;Galectin-3;IgE-binding protein;L-31;Laminin-binding protein;Lectin L-29;LGALS 3;LGALS3;Mac-2 antigen

Gene names:LGALS3

Standard solution:2400pg/ml