Human Follistatin-related protein 3,FLRG ELISA KIT

SKU: E3691Hu

Size:96 Tests-1 Kit

Background:Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10. {ECO:0000269|PubMed:11948405, ECO:0000269|PubMed:15451575, ECO:0000269|PubMed:15574124, ECO:0000269|PubMed:16336961, ECO:0000269|PubMed:17868029, ECO:0000269|PubMed:17878677}.

Research_area:

Applications:ELISA

Target_protein:FSTL3

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.23ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Follistatin-related gene

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95633

MASS(Da):27663

GeneID:10272

Synonyms:FSTL3 FLRG UNQ674/PRO1308

Gene names:FSTL3

Standard solution:4800ng/L