Human Ficolin 1, FCN1 ELISA Kit

SKU: E3143Hu

Size:96 Tests-1 Kit

Background:Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed: 21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

Research_area:Others

Applications:ELISA

Target_protein:FCN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.92ng/ml

Detection range:2-600ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ficolin 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00602

MASS(Da):35,078

GeneID:2219

Synonyms:Collagen/fibrinogen domain-containing protein 1;FCN 1;FCN1;Ficolin-1;Ficolin-A;Ficolin-alpha;M-ficolin

Gene names:FCN1

Standard solution:800ng/ml