Human Ets-related Transcription Factor Elf-3, ELF3 ELISA Kit

SKU: E6473Hu

Size:96 Tests-1 Kit

Background:Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:ELF3

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.74ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ets-Related Transcription Factor Elf-3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P78545

MASS(Da):41,454

GeneID:1999

Synonyms:E74-like factor 3;ELF 3;ELF3;Epithelial-restricted with serine box;Epithelium-restricted Ets protein ESX;Epithelium-specific Ets transcription factor 1;ESE-1;ETS-related transcription factor Elf-3

Gene names:ELF3

Standard solution:1600ng/L