Human E-Cadherin, E-CAD ELISA Kit

SKU: E0209Hu

Size:96 Tests-1 Kit

Background:Cadherins are calcium-dependent cell adhesion proteins (PubMed: 11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed: 11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.

Research_area:Cancer

Applications:ELISA

Target_protein:CDH1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.52ng/ml

Detection range:1-300ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:E-Cadherin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P12830

MASS(Da):97,456

GeneID:999

Synonyms:Cadherin-1;CAM 120/80;CD antigen CD324;CDH 1;CDH1;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3;E-cadherin;Epithelial cadherin;Uvomorulin

Gene names:CDH1

Standard solution:400ng/ml