Human DNA Repair Protein Rad51 Homolog 1, RAD51 ELISA Kit

SKU: E1370Hu

Size:96 Tests-1 Kit

Background:Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed: 28575658). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed: 26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair (PubMed: 26253028).

Research_area:Others

Applications:ELISA

Target_protein:RAD51

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.11ng/ml

Detection range:0.2-70ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dna Repair Protein Rad51 Homolog 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q06609

MASS(Da):36,966

GeneID:5888

Synonyms:DNA repair protein RAD51 homolog 1;hRAD51;HsRAD51;RAD51;RAD51 homolog A

Gene names:RAD51

Standard solution:80ng/ml