Human Dickkopf-3,DKK3 ELISA KIT

SKU: E2065Hu

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:DKK3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.22ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UBP4

MASS(Da):38390

GeneID:27122

Synonyms:DKK3 REIC UNQ258/PRO295

Gene names:DKK3

Standard solution:64ng/ml